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March 31, 2009

The PILL pilot trial (3)

Can you believe it? Just days after I become involved in a trial of the so-called "polypill", this morning the "Mirror" newspaper - for no apparent reason - runs a story on this new form of medication.

Footnote: Now that I've seen more of today's media, I see why the "polypill" is in the news today. It's because of the presentation of a paper yesterday at the American College of Cardiology annual conference - see this report in the "Guardian" - and the publication of a paper in the "Lancet" - see this summary.

A special view of China

Take your time and 'walk through' this Chinese painting which stretches across some length. At each of the three white boxes, turn on your sound system, click your mouse within the box, and you will be amazed at how the painting comes to life. Cursor to right to fast forward. Enjoy!

This is a very famous painting in China . People line up for hours at the Shanghai Museum just to view it. This painting was originally painted, circa 1085-1145, during the Northern Song Dynasty. It was repainted during the Qing Dynasty. It measures 528cm in width and 24.8cm in height.

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Forgotten World (167): Azerbaijan

Azerbaijan gained its independence in 1991 as a result of the break-up of the former Soviet Union. It is an oil-rich state and in 1994 signed an oil contract worth $7.4bn with a Western consortium. Since then Western companies have invested millions in the development of the country's oil and gas reserves. Caspian oil is now flowing through a pipeline running from Baku through Georgia to the Turkish port of Ceyhan, providing western countries with ready access to a vast new source of supply. However, the economy as a whole has not benefited as much as it might have done and living standards among the 8 million Azerbaijanis are low.

As the Soviet Union collapsed, the predominantly Armenian population of the Nagorno-Karabakh region stated their intention to secede from Azerbaijan. War broke out. Backed by troops and resources from Armenia proper, the Armenians of Karabakh took control of the region and surrounding territory. In 1994 a ceasefire was signed. About one-seventh of Azerbaijan's territory remains occupied, while 800,000 refugees and internally displaced persons are scattered around the country.

March 30, 2009

The PILL pilot trial (2)

This morning, together with my wife, I made a second visit to the International Centre for Circulatory Health at St Mary's Hospital at Paddington in London to be considered for participation in a pilot trial for a "polypill" to treat people at raised risk of cardiovascular disease such as as heart attack or stroke.

We had our blood pressure tested another three times and then all the data from the two visits was fed into a computer to assess our suitability for the trial. My wife was judged too healthy for inclusion, but I was judged to have a marginal level of risk that justified me being in the trial. So I was given a packet of pills which I have to take each day at dinner time. Of course, I don't know whether I'm taking the real pill or a placebo and indeed nobody will know that until the conclusion of the 12-week trial.

Forgotten World (166): Bavaria

It's time to have another week of postings in my long-running series called Forgotten World - a look at parts of the world that hardly feature in our media or thoughts. You can check the previous 165 entries here.

Bavaria - located in the south-east of Germany - is the largest of the 16 Lander that make up the German nation and its capital is Munich. On its own, the Land of Bavaria has a population of 10.5 million which makes it as big as many nation states in Europe. It has long had one of the largest and healthiest economies of any region in Germany or Europe for that matter and its GDP in 2007 exceeded 434 billion Euros (about $600 billion) making it one of the largest economies in Europe and the 18th largest in the world.

Politically Bavaria is very distinctive as well. The conservative Christian Social Union of Bavaria (CSU) has dominated politics since 1957 and won every election since then. The federal conservative party the Christian Democratic Union of Germany (CDU) does not operate in Bavaria and the CSU acts as the CDU's sister party there and they form a single faction in the Federal parliament. The difference between the CDU and the CSU is mainly that the CSU is more conservative in domestic and social issues but more progressive in fiscal issues.

March 26, 2009

Off to Lisbon

I'm off to Lisbon for a couple of days to speak at a seminar organised by the Portuguese regulator for posts and telecommunications. I'll be describing the operation of the Communications Consumer Panel in the UK on which I have served since it was created five years ago.

It will be my fourth visit to Lisbon and I hope to have a little time to look around. I love the place as you'll see from this note.

The PILL pilot trial (1)

You read about medical trials but this is the first time that I've had any personal involvement in one. This morning, together with my wife, I spent an hour and a half at the International Centre for Circulatory Health at St Mary's Hospital at Paddington in London being considered for participation in a pilot trial which will lead on to a long-term clinical trial.

The research study is of the efficacy of a combination medication called the "polypill" - which contains aspirin, a statin, and two blood pressure lowering medicines - compared to a placebo in treating people at raised risk of cardiovascular disease such as as heart attack or stroke. Rather neatly, the trial is called PILL which stands for Programme to Improve Life and Longevity.

We were asked not to eat or drink anything for the 12 hours prior to our 10.30 am appointment. Following an explanation of the trial and signing of a consent form, I was asked lots of questions about my health and lifestyle and then my blood pressure was taken three times, a blood sample was taken, my height and weight were measured, and my body mass index was calculated.

If I'm found to be too healthy, I won't be included in the 12-week trial; if I'm found to be too much at risk, I won't be included either; if I'm found to have a modestly increased level of risk (my mother had a stroke at 69), I will be included.

Some more information here.

March 24, 2009

The shah of Iran

This week, I was able to visit the British Museum and see the fascinating exhibition "Shah 'Abbas: The Remaking of Iran". This tells the story of seventeenth-century Iran through the reign and legacy of one of its most influential rulers, Shah 'Abbas I who reigned 1587–1629 and founded the capital of Isfarhan.

I would always have been interested in this exhibition because I am keen on Middle Eastern history and Islamic architecture, but I was especially attracted to the event because I hope that we will holiday in Iran in the Autumn.

March 22, 2009

What does the name Pakistan mean?

The name Pakistan means "Land of (the) Pure" in Urdu and Persian (Farsi). It was coined in 1934 as Pakstan by Choudhary Rahmat Ali, who published it in his pamphlet "Now or Never". The name represented the "thirty million Muslims of PAKISTAN, who live in the five Northern Units of the British Raj — Punjab, Afghania (also known as North-West Frontier Province), Kashmir, Sindh, and Balochistan."

Now best-selling British novelist Jeffrey Archer is in trouble with his latest work "Paths of Glory". There are complaints about the book's final section, in which the murder of Lt Col Henry Morshead, a real figure, is blamed on his sister's "Pakistani lover" in 1931. As the press attache to the Pakistani High Commission in London has pointed out: "Pakistan was not created in 1931 so there is no possibility of a Pakistani at that time."

As we have seen, the term was first proposed in 1934 - but the country did not come into existence until 14 August 1947.

March 21, 2009

How to prepare for death

I've run a web site for almost 10 years now and, ever expanding in content, it now has almost 140 sections. One of the most popular areas of the site is the set of pages on life skills.

I've just created the 27th page in this life skills section. It's called "How To Prepare For Death" - practical rather than cheerful.

March 19, 2009

What's the future for divided nations?

I recently took a cab in London driven by a Tamil exile from Sri Lanka and we discussed the decades long conflict on that island. He surprised me by suggesting that the war was the result of Britain granting independence to what was then Ceylon as a single nation state in 1948 (it was renamed Sri Lanka in 1972).

He said that Britain should have done what it did in India where it attempted to separate out most of the Muslims into Pakistan leaving India as predominantly Hindu. In his view, Ceylon should have been divided into two states - one mainly Sinhalese and the other Tamil.

Of course, as I blogged here, the partition of India involved an horrific price: communal riots resulting in the death of around half a million and the displacement about 14.5 million, followed later by the war between west and east Pakistan, and the failed state that Pakistan continues to represent. If Ceylon had been divided, would it have fared better than has been the experience of Sri Lanka when some 60,000 have died in the long-running war?

I have speculated about the nature of nationhood and the resolution of ethnic conflict in an essay on my web site here.

March 18, 2009

Back from Gateshead

I've just returned from a short trip to Gateshead in the north-east of England where, on behalf of the Communications Consumer Panel, I made a presentation at a conference on next generation broadband.

The event was held in the Gateshead Council Chamber where I found myself sitting in the seat normally occupied by the Leader of the Opposition (a Liberal Democrat - there have never been any Tories on the Council!) and admiring a banner of the National Union of Mineworkers (don't imagine that's very common in other town halls).

On the trains to and from Newcastle, I could see the monumental Angel of the North. The conference was held in the Gateshead Civic Centre which contains a small scale replica of the Angel of the North which apparently featured on the "Antiques Roadshow" television series where it was valued at £1 million.

Since I spent the night previous to the event in Gateshead, I was able to have dinner with my good friend Mavis Smith. We both used to work for communications trade unions in the telecoms sector, but I had not seen her in the 11 years since she retired.

So it was a trip in which I was able to combine the professional and the personal.

March 17, 2009

I'm off to Newcastle ...

... to speak at a conference in Gateshead tomorrow.

Maybe, while I'm passing through Newcastle, I'll see a flaming horse, a singing humanoid or fighting machines, all of which can be found at Newcastle's Maker Faire. Check it out here.

March 16, 2009

The scandal of fuel poverty

  • 5 million households in Britain shiver through winter because their homes are so poorly insulated they cannot afford to heat them.
  • Over 1 million older people have to choose between eating and heating.
  • 1 in 3 older people are forced to live in only one room of their home.
  • Britain’s homes leak twice as much heat and power as homes in Nordic countries – meaning higher fuel bills and more CO2 emissions.
  • 1,400,000 children’s lives are blighted: it affects their education and their friendships.
  • Fuel poverty costs the health service £1.9 billion every year.
  • That means an average £2.9 million annual waste in your area.
This Friday, your Member of Parliament has the chance to end this scandal by voting for the Fuel Poverty Bill. Please contact them today to insist they do just that.

March 15, 2009

Has Spring sprung at last?

For the first time this year, it was mild enough for us to have lunch on our terrrace.

Why didn't they tell us?

It wasn't just the regulators who failed totally to control the absurdities of the market that led to the credit crunch; financial journalism failed big time and most financial commentators were complicit in the myth making that deluded ordinary borrowers and investors.

Over in the United States, Jon Stewart has done a brilliant job on "The Daily Show" - which has a global edition (see it on More4 in the UK) - in exposing this failure and most especially savaged Jim Cramer for his unforgivable role in all this.

You can start viewing the three-part clip of the interview here:

You can read the background to this encounter here.

March 14, 2009

Are you having a laugh?

These are serious times, but we all need a laugh from time to time, so remember that there's lots of jokes on my web site here and here.

March 12, 2009

Social networking overtaken e-mail

"Social Networking has been the global consumer phenomenon of 2008. Two-thirds of the world’s Internet population visit a social network or blogging site and the sector now accounts for almost 10% of all internet time. ‘Member Communities’ has overtaken personal Email to become the world’s fourth most popular online sector after search, portals and PC software applications."
Who say's so? Nielson in this report.

March 11, 2009

Illuminating the nonsensical

Feeling a bit down or confused in these troubled times?

Maybe you need some help from "the Beings of Light in the Realms of Illumined Truth". Don't know about them? All will be revealed here.

If you think this is nonsensical or even weird, you might ask yourself: why do people believe such weird things? I've offered 36 suggestions here.

You choose. Does it matter? I've explained why I think truth matters here.

March 10, 2009

Whatever happened to democratic socialism?

A former professor at the London School of Economics has contacted me to ask about a discussion we had when I was Special Adviser to the Home Secretary in 1977. Now I don't know about you, but I can't remember details of meetings which I had 32 years ago - but I have kept a daily diary since I was 13, so I was able to do some checking for him.

While looking at my diary for 1977, I came across this entry: "I took a taxi to Wanstead House for my speech to Wanstead Branch Labour Party. At 9 pm, I gave a 40-minute speech entitled 'The Future Of Democratic Socialism' in which I examined the elimination of poverty, the redistribution of income & wealth, economic planning, public ownership, individual rights, internationalism and democracy."

I can't be absolutely sure after all this time, but I'm fairly confident that I didn't mention nationalisation of the banks - that would have been far too radical. I wonder though: do Labour Party Branches still have this kind of discussion? I doubt it.

Incidentally I see that, over in the United States, the Republicans have decided that calling Barack Obama "a liberal" is too mild, so now they are accusing him of being "a socialist" and even the "New York Times" has got into the act [see here]. So it looks as if I'm in good company.

March 09, 2009

What next for the British economy?

"Once in a generation you have an opportunity to change society in profound ways. For all the hardship and insecurity bound up in recent events, we are lucky to live in such a moment. What seemed infallible until recently – the essential credo behind the last 30 years of economic history – has crumbled, like communism before it. Yet this is not a crisis of capitalism, but a crisis of a society and democracy that have failed to regulate the market. It will become a crisis for our planet, too, unless we resolve it."
This is the conclusion of a thoughtful piece on the current financial crisis written for the "New Statesman" by Compass Chairman Neal Lawson and "Guardian" John Harris.

The pressure group Compass has created a short video to make the case for change:

March 08, 2009

How should judges be chosen?

Following a suggestion from a reader in Taiwan, I've added a paragraph to my web essay on "A Short Guide To The American Political System" to point out that, below federal level, the overwheming majority of American judges are elected whereas, in virtually every other country, they are selected in some way.

Nationwide 87% of all state court judges are elected and 39 states elect at least some of their judges. Outside of the United States, however, there are only two nations that have judicial elections and then only in limited fashion. Smaller Swiss cantons elect judges and appointed justices on the Japanese Supreme Court must sometimes face retention elections (although those elections are a formality).

You can read more about the American system of electing judges and the advantages and disadvantages of this system in this "New York Times" article.

March 07, 2009

"The Day After Peace"

This evening, Vee and I visited our dear young friends Rachael and James for dinner and discussion. Together we watched a DVD of a remarkable and inspiring documentary entitled "The Day After Peace".

Featuring Jude Law, Angelina Jolie, the Dalai Lama, Annie Lennox, Kofi Annan and Jonny Lee Miller, the documentary charts the astonishing 10-year journey of award-winning filmmaker Jeremy Gilley to establish an annual Peace Day on 21 September.

It shows the power of campaigning, even against formidable odds, when the campaigners refuse to give up and political, business and celebrity allies come on board.

Incidentally both Rachael and James are incredibly creative people, she as a ceramicist and he as a furniture designer. Rachael has just opened a web site here.

March 06, 2009

It has been much worse

I know that everyone is now suffering the impact of the global economic crisis and that some people have been hit much harder than others. But it is important to keep a sense of perspective.

I'm currently reading "A History Of Modern Britain" by Andrew Marr (born 1959) which is essentially a review of the last six decades or so since the end of the Second World War. Since I'm now 60, this is more or less coincident with my own life experience.

What has really struck me about the early sections of the book - especially because I was too young to remember the times - was the longevity and impact of rationing in Britain. It started in 1940 and you can read some of the detail here. I think younger British readers and all my American readers will be astonished at the privations experienced by the British at that time.

But it continued long after the end of the war. Fourteen years of food rationing in Britain ended at midnight on 4 July 1954, when restrictions on the sale and purchase of meat and bacon were lifted. The war had been over nine years and I was aged six.

Do you remember rationing? What was it like?

March 05, 2009

World Book Day

You may not have noticed it but today is World Book Day.

Now, all my life, I have loved books and on my web site you can find some 165 book reviews.

My night with the stars

As a massive movie fan, my dream is to attend a BAFTA or Academy Awards ceremony and mix with famous actors and actresses. It hasn't happened yet, but last night I suppose a had a little taste of what it might be like.

I was a guest of the Post Office at an event which they co-sponsored with Barnardo's and the "News Of The World" newspaper held at the Grosvenor House Hotel on Park Lane in central London. Some 300 people attended the Children's Champions 2009 Awards.

I am now going to shamelessly 'name drop' in a manner that I've never done with any previous blog posting, so forgive me.

The hosts for the event were Shane Richie (ex "EastEnders") and Emma Bunton (the nice Spice Girl). The presenters of the awards included Prince Andrew, Jane Torville and Christopher Dean, Lord Seb Coe, Kelly Holmes, Paul O'Grady, Ros Kemp, Amanda Holden and Melinda Messenger. Sitting on my table were of Graham Cole of "The Bill" and Danielle Lloyd of "Celebrity Big Brother".

Of course, the real stars of the ceremony really were the people who received the awards and each of their stories was incredibly moving.

March 02, 2009

How was humankind created?

"It is intriguing that 37% of people believe that humans evolved by a process of evolution which removes any need for God. 28% of people think that humans evolved by a process of evolution which can be seen as part of God’s plan. 11% believe in Intelligent Design (the idea that humans evolved by a process of evolution which required the special intervention of God or a higher power at key stages) and 17% believe that human beings were created by God some time within the last 10,000 years."
This is an extract from a piece by the British think tank Theos commenting on a survey which the organisation commissioned on the beliefs of people across the UK. The "Guardian" has turned the results into a map so that you can see the variation in belief across nations and regions of the UK.

Me? I'm firmly in the 37% category.

March 01, 2009

Controversy over "The Reader"

If you haven't read the novel "The Reader" by Bernhard Schlink or seen the film starring Kate Winslet, my discussion of the moral core of the story may not interest you and, if you intend to read the book or see the film, you might not want to spoil things by reading what follows in this blog entry.

On the other hand, if you've read the novel and/or seen the film, you might be interested in the following discussion of what Schlink is trying to do.

My review of the book

When I saw the film of "The Reader", I admired the brilliant acting by Kate Winslet but was disturbed by the moral confusion of the story by German law professor Berhard Schlink. I decided ro read the best-selling book to see if the moral issue became any clearer. This is a Holocaust work that attempts to explore the hugely sensitive issue of the guilt of the following German generation. It is a quick read since it is not a long work and the chapters are all unusually short - but does it make the moral question any clearer?

The first two-fifths of the story - located in 1958 - is about the relationship between 36 year old tram conductor Hanna Schmitz and 15 year old schoolboy Michael Berg; the second two-fifths - set seven years later - revolves around the trial of Hanna witnessed by Michael; and the final fifth or so concerns the time of Hanna's 18 year prison sentence.

What I found was that the movie is a faithful adaptation of the novel. Schlink's relatively sparse but moving writing is perhaps more revealing of Michael's thoughts about Hanna (frequent references to him feeling "nothing" and his "numbness") but no less illuminating about Hanna's motivations and feelings (twice she cries "What would you have done?" and seems to exhibit emotional autism).

The reader of the title is, at different times, Michael, Hanna and we ourselves. For me, the key sentence of the book is Michael's dilemma: "I wanted to pose myself both tasks - understanding and condemnation. But it was impossible to do both." Arguably most Holocaust literature has been more about condemnation than understanding, but Schlink runs the risk of showing more understanding than condemnation. Surely one has to do both, however difficult, and it is immensely difficult.


A comment on this review from an American Jewish friend

If I recall correctly, over time Hanna took several young women prisoners under her charge, provided special care for them in her hut, as long as they read to her and their number had not yet come up in the "selection." When that happened she turned them back into the mass (or was it when she tired of anyone of them?) for murder by gassing. Somehow the film script left this out - as it can complicate our difficulty in "judging" her.

Hanna's caring for some reader-prisoners would seem somewhat of an answer to the question she posed to the Judge - "What would you have done?" - in that she seems to have provided a brief warm respite (a short stay in her hut rather than a fatal moment in the gas chamber) for as many women as she could - probably to the consternation of the other (literate) camp guards (who probably only thought of this as a lesbian arrangement - like some such forced liaisons they may have enjoyed).
I note your comment does not mention Hanna's suicide, seemingly her own unforgiving judgment on her crimes: what do you make of it, and, its place in the scheme of the book's wrestling with "big questions."?

Finally, I agree that both/and thinking and feeling - while almost always more demanding and even enervating - generally trumps either/or thinking in matters as grave as these.


My response to my friend's comment

You remember correctly about Hanna's selection of young women readers in the camp. One interpretation of her conduct - that apparently favoured by Michael - is that she was showing them a kindness as long as she could. Another interpretation is that she was simply using them as readers as long as she could. She might have used them as lovers too - we don't know. When she later meets Michael, she could have simply befriended him and asked him to read to her - small thanks for the kindness she showed when he was ill. But she immediately had sex with him and never indicated that she loved him. Both her conduct in the camp and with Michael can be seen as predatory and selfish acts.

I don't mention the suicide in my review because I feel that would spoil the book for somebody who has not read it. Again different interpretations are possible. The first is the one you suggest: unforgiving judgment on herself. But, if she was consumed with guilt, she could have committed suicide at any point in her 18 year sentence and she never expressed guilt in her dealings with others in the prison or in her letters to Michael. A second interpretation is that she had become institutionalised from 18 years in prison and did not feel that she could cope outside or that she was afraid that outside she would be judged for her crimes by the people she would have to meet. Either way this would make her suicide a selfish act rather than a redeeming one.

Hanna's shame about her illiteracy explains why she volunteered to be a camp guard, why she befriended Michael, why she left her job at the tram company, and why she admitted to writing a report on the church fire that she was incapable of writing. Schlink seems to be suggesting that this explains her actions and should make us the reader understanding. But at no point does Hanna show any indication that she was making moral choices with consequences of life and death. She seems obsessed with practical issues without any understanding of the moral context which is why I suggest in my review that she exhibits a form of emotional autism.


So, what do you think?